Obesity and metabolic syndromes, including liver disorders and type 2 diabetes, are epidemic worldwide and are closely related to diet & nutrition. Microorganisms in the gut microbiota influence energy metabolism and the immune system and have been the subject of ongoing research in the treatment of obesity and related metabolic diseases.
In terms of next-generation probiotics (beneficial microorganisms), Akkermansia muciniphila (A. muciniphila) colonizes the mucosal layer of the gut and can modulate basal metabolism. A. muciniphila is a probiotic that has been associated with obesity and its therapeutic beneficial effects in obesity have been proven by studies. Characterized as a beneficial player in body metabolism, A. muciniphila is anticipated as a new generation of therapeutic agents in obesity and diseases associated with metabolic disorders